- Product Name
- CasNo
- MF
- MW
- Content
- Appearance
- Packing
- Apply
- Dehydroepiandrosterone
- 53-43-0
- C<sub>19</sub>H<sub>28</sub>O<sub>2</sub>
- 288.43
- white fine crystalline powder
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Dehydroepiandrosterone(DHEA) is an endogenous steroid hormone that is secreted primarily by the adrenal gland and is the most abundant sex steroid. It is a neurohormone; small quantities of DHEA are produced in the brain and declines in serum and CSF with age. (Knopman and Henderson, 2003). Metabolites of DHEA include androstenedione , which subsequently may be metabolized to testosterone or estrone which is an estradiol precursor. In addition to serving as an intermediate in the biosynthesis of sex steroids, DHEA directly modulates a number of cellular and nuclear receptors.
Dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome. People living with HIV may be interested in taking DHEA for a variety of reasons, including treatment of depression, increasing bone density, decreasing arterial plaques, improvement of immune function with HIV, increased memory, and increased muscle strength.
The CAS number of Dehydroepiandrosterone is 53-43-0.
More information of Dehydroepiandrosterone 53-43-0 are:
|
CAS Number |
53-43-0 |
|
Density |
1.12 g/cm3 |
|
Melting Point |
149-151 °C(lit.) |
|
Boiling Point |
426.7 °C at 760 mmHg |
|
Flash Point |
182.1 °C |
|
Vapor Pressure |
4.54E-09mmHg at 25°C |
|
Refractive Index |
1.4709 (estimate) |
|
HS CODE |
29372900 |
|
PSA |
37.30000 |
|
LogP |
3.87920 |
|
Pka |
15.02±0.60(Predicted) |
The chemical formula of Dehydroepiandrosterone is C19H28O2 which containing 19 Carbon atoms,28 Hydrogen atoms and 2 Oxygen atoms,and the molecular weight, and the molecular weight of Dehydroepiandrosterone is 288.43
Dehydroepiandrosterone(DHEA) is an endogenous steroid hormone that is secreted primarily by the adrenal gland and is the most abundant sex steroid. It is a neurohormone; small quantities of DHEA are produced in the brain and declines in serum and CSF with age. (Knopman and Henderson, 2003). Metabolites of DHEA include androstenedione , which subsequently may be metabolized to testosterone or estrone which is an estradiol precursor. In addition to serving as an intermediate in the biosynthesis of sex steroids, DHEA directly modulates a number of cellular and nuclear receptors.
InChI:InChI=1/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h3,13-16,20H,4-11H2,1-2H3/t13-,14-,15?,16?,18-,19-/m0/s1
Relevant articles related to Dehydroepiandrosterone:
|
Article |
Source |
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Synthesis and structure determination of 3β-hydroxyandrost-5-en-17-one (C19H28O2·CH3OH) |
Verma, Rajnikant,Jasrotia, Dinesh,Sawhney, Anshu,Bhat, Mousmi,Gupta , p. 523 - 528 (2004) |
|
Modified bile acids and androstanes—Novel promising inhibitors of human cytochrome P450 17A1 |
Dzichenka, Yaraslau,Shapira, Michail,Yantsevich, Aliaksei,Cherkesova, Tatsiana,Grbovi?, Ljubica,Savi?, Marina,Usanov, Sergey,Jovanovi?-?anta, Suzana , (2020/11/17) |
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